Apoptosis - programmed cell death.
Proto-oncogenes - normal cellular genes that contribute to the production of cancer when their activity is affected.
Stochastic hypothesis - virtually any cell type could become transformed given the occurrence of a proto-oncogene mutation.
Cancer stem cell (CSC) - tumorigenic cell possessing stem cell-like properties that has the ability to give rise to all cell types of a given cancer.
Embryonal rest hypothesis - Hypothesis of Rudolph Virchow that tumors arise from residual embryonic tissues.
Select key terms are defined below. For a complete list of glossary terms please refer to the book.